Part of the Peptivitalis Compound Index.
Statements under Research findings describe published research on the molecule. They are not statements about the properties, effects or suitability of anything Peptivitalis supplies, and they are not guidance for use in humans or animals. Every finding names the model system it came from, and the limits of the evidence are stated alongside it.
Epithalon
Identity
| CAS | 307297-39-8 |
| Molecular weight | 390.3 g/mol |
| Sequence | Ala-Glu-Asp-Gly (tetrapeptide) |
| Also known as | Epitalon |
Research findings
- A synthetic tetrapeptide derived from work on pineal gland extracts
- Proposed mechanisms in the source literature centre on regulation of gene expression and telomerase activity
- Examined in preclinical ageing research conducted by the originating institute
- No independent replication identified, and no controlled human trials meeting conventional international standards identified
- Not an approved medicine in any jurisdiction
We treat this entry with more caution than the others, and you should know why.
The published literature on Epithalon originates almost entirely from a single research group and appears largely in Russian-language or Russian-affiliated journals. We have not identified substantial independent replication by unaffiliated groups in the mainstream international literature.
That is not a statement that the work is wrong. It is a statement about the structure of the evidence base, and it is materially different from compounds such as BPC-157 or MOTS-c where multiple independent laboratories have published. We list no citations here rather than present single-source material as though it carried the same weight as the rest of this index.
Research focus
- Telomerase activity in cell culture
- Pineal and melatonin regulation
- Peptide bioregulator research
- Experimental gerontology
Availability and handling
Lyophilised powder. Store at 2–8 °C, protected from light. Specification: ≥98% by RP-HPLC; identity by mass spectrometry.
Availability: 10 mg · SKU ET10